DYRK2, active, GST tagged human,10UG,SRP5326-10UG,Sigma

销售价: ¥ 3866.08 / 件
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订货号 0BU0223
品牌型号 Sigma SRP5326-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

DYRK2 (also known as dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2) belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development and is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 expressed in E. coli demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. DYRK2 also regulates p53 to induce apoptosis in response to DNA damage.


Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.


Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.


Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
recombinantexpressed in E. coli
product linePRECISIO®
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
specific activity1000-1500 nmol/min·mg
mol wt ~95 kDa
NCBI accession no.NM_006482
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... DYRK2(8445)
长度(mm)
宽度(mm)
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重量(kg)
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