抗-白血病抑制因子单克隆抗体小鼠抗，500UG，L0669-500UG，Sigma

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订货号： 0BT9999

品牌型号： Sigma L0669-500UG

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最小订货量： 1件

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商品介绍
规格参数
包装参数

产品介绍 Product Description

Immunogen

purified, E. coli-derived recombinant human leukemia inhibitory factor.

Biochem/physiol Actions

Leukemia inhibitory factor (LIF) is a pleotrophic glycoprotein that belongs to the IL-6 family of cytokines. It is secreted by many cell types such as, fibroblasts, macrophages, T cells, monocytes, liver cells, osteoblasts and cells of endometrium. A variety of signal transduction pathways are triggered in response to LIF including ERK/MAPK, JAK1, PI3K, STAT3, Jun-c Fos and NF-κB. The various functions of LIF include proliferation of adult human T cells, maintenance of pluripotency of embryonic stem cells and inhibition of leukemic cell differentiation.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	mouse
Quality Segment	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	9824, monoclonal
form	lyophilized powder
species reactivity	human
technique(s)	capture ELISA: 2-4 μg/mL,immunohistochemistry: 25 μg/mL,neutralization: suitable,western blot: 1-2 μg/mL
UniProt accession no.	P15018
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... LIF(3976)