Anti-Matrix Metalloproteinase-24, Cytoplasmic antibody produced in rabbit，100UG，M6559-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Matrix metalloproteinase-24 (MMP-24) is mainly expressed in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20.

Immunogen

synthetic peptide corresponding to the cytoplasmic domain of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5)

Biochem/physiol Actions

Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.
Reacts with native and reduced MMP-24. The antibody recognizes the pro-form of MMP-24 as well as activation/breakdown products. The cytoplasmic domain of MMP-24 is detached when MT-MMPs shed from themselves, thus this antibody should not detect this form of MMP-24.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Segment	200
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous glycerol solution
mol wt	antigen 65 kDa
species reactivity	mouse, human
concentration	~1 mg/mL
technique(s)	flow cytometry: suitable,immunohistochemistry (frozen sections): suitable,immunoprecipitation (IP): suitable,indirect ELISA: suitable,western blot: 1:2,000
UniProt accession no.	Q9Y5R2
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... MMP24(10893) mouse ... Mmp24(17391)

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