ASP7663,5MG,SML1467-5MG,Sigma

销售价: ¥ 1347.72 / 件
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订货号 0BT8470
品牌型号 Sigma SML1467-5MG
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最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.
ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1).


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
colorlight orange to dark orange
solubilityDMSO: 25 mg/mL, clear
storage temp.2-8°C
SMILES stringCC(C)CN(C1=C(F)C=CC=C1/C2=C\C(O)=O)C2=O
InChI1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+
InChI keyRCVZUIGCNAAMIC-UXBLZVDNSA-N
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