Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human,50UG,T3439-50UG,Sigma

销售价: ¥ 5878.69 / 件
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订货号 0BT7222
品牌型号 Sigma T3439-50UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human may be used to study signaling of apoptosis and NF-κB activation.


Biochem/physiol Actions

Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human belongs to TNF family of receptors and has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β. Soluble tumor necrosis factor receptor along with intrathecal interleukin-1 receptor antagonist shows an anti-allodynic action in rat L5 spinal nerve transection model of neuropathic pain.


Physical form

Lyophilized from 0.2 um-filtered solution in PBS, pH 7.4 with 50 µg BSA.


Analysis Note

The biological activity is measured by its ability to neutralize apoptosis of mouse L-929 cells treated with 0.25 ng/ml recombinant human TNF-α.


技术参数 Specifications
biological sourcehuman
Quality Segment100
recombinantexpressed in NSO cells
assay≥95% (SDS-PAGE)
formlyophilized powder
potency0.4-2 ng/mL ED50
mol wt 48 kDa
packagingpkg of 50 μg
storage conditionavoid repeated freeze/thaw cycles
technique(s)cell culture | mammalian: suitable
impurities endotoxin, tested
UniProt accession no.P20333
storage temp.−20°C
Gene Informationhuman ... TNFRSF1B(7133)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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