- 商品介绍
- 规格参数
- 包装参数
Application
Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human may be used to study signaling of apoptosis and NF-κB activation.
Biochem/physiol Actions
Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human belongs to TNF family of receptors and has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β. Soluble tumor necrosis factor receptor along with intrathecal interleukin-1 receptor antagonist shows an anti-allodynic action in rat L5 spinal nerve transection model of neuropathic pain.
Physical form
Lyophilized from 0.2 um-filtered solution in PBS, pH 7.4 with 50 µg BSA.
Analysis Note
The biological activity is measured by its ability to neutralize apoptosis of mouse L-929 cells treated with 0.25 ng/ml recombinant human TNF-α.
| biological source | human |
| Quality Segment | 100 |
| recombinant | expressed in NSO cells |
| assay | ≥95% (SDS-PAGE) |
| form | lyophilized powder |
| potency | 0.4-2 ng/mL ED50 |
| mol wt | 48 kDa |
| packaging | pkg of 50 μg |
| storage condition | avoid repeated freeze/thaw cycles |
| technique(s) | cell culture | mammalian: suitable |
| impurities | endotoxin, tested |
| UniProt accession no. | P20333 |
| storage temp. | −20°C |
| Gene Information | human ... TNFRSF1B(7133) |
| 长度(mm) | |
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| 重量(kg) |




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