Anti-Human IgG (γ-chain specific), F(ab′)₂ fragment−R-Phycoerythrin antibody produced in goat,0.5ML,P8047-.5ML,Sigma

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订货号 0BT6971
品牌型号 Sigma P8047-.5ML
货期 询货期
最小订货量 1件
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  • 商品介绍
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产品介绍 Product Description

General description

IgG is a glycoprotein antibody that contains two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4.


Immunogen

Purified human IgG


Application

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment R-Phycoerythrin antibody produced in goat has been used in bead-based assay and immunoassay multiplex magpix
Anti-Human IgG (γ-chain specific), F(ab′)2 fragment-R-Phycoerythrin antibody is suitable for use in flow cytometry . The antibody can also be used for direct immunofluorescence (1:32).


Biochem/physiol Actions

Digestion of IgG by papain results in generation of fragment antigen binding (Fab) comprising of one complete L chain and a variable and CH1 region of H chain. Pepsin digestion of IgG results in fragment crystallisable (fc), comprises the H chain constant region.
IgG antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders . The use of anti-human IgG (γ-chain specific), F(ab′)2 fragment-R-Phycoerythrin antibody helps avoid background staining due to the presence of Fc receptors. The product is specific for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones κ, and Bence Jones λ myeloma proteins.


Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 0.1 mM EDTA, 1 mM iodoacetamide, 1% bovine serum albumin and 15 mM sodium azide


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcegoat
Quality Level200
conjugatephycoerythrin (R-PE) conjugate
antibody formaffinity isolated antibody
antibody product typesecondary antibodies
clonepolyclonal
formbuffered aqueous solution
technique(s)direct immunofluorescence: 1:32
shipped inwet ice
storage temp.2-8°C
target post-translational modificationunmodified
长度(mm)
宽度(mm)
高度(mm)
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