Anti-Cadherin 16 Antibody, clone 2J0H4, Rabbit Monoclonal,100UL,SAB5702932-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 : 0BT5897
品牌型号 : Sigma SAB5702932-100UL
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]


Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 50-180 of human Cadherin 16 (O75309).


Application

WB, IF/ICC


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone2J0H4, monoclonal
formliquid
mol wt 120 kDa
species reactivitymouse
concentration0.10 mg/mL
technique(s)immunofluorescence: 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceGAEGQIVLSGDSGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDENDQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
UniProt accession no.O75309
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CDH16(1014)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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