Anti-SIRT5 antibody produced in chicken，100UG，SAB3500496-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

SIRT5 (Sirtuin 5) is a mitochondrial matrix protein belonging to the class III of the sirtuin family. It is localized inside the mitochondria and within the cytosol and nucleus. The protein is widely expressed in the brain, heart, liver and kidney. It is composed of very short amino and carboxyl terminal sequences flanking region with the conserved, catalytic sirtuin center domain.

Immunogen

SIRT5 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SIRT5.

Application

Anti-SIRT5 antibody produced in chicken is suitable for western blot and indirect ELISA.

Biochem/physiol Actions

SIRT5 (Sirtuin 5) is associated with metabolism and aging process. It has been reported in a study that SIRT5 influences urea cycle pathway by NAD-dependent deacetylation and subsequent activation of carbamoyl phosphate synthetase 1 (CPS1), which plays a vital role in the initial step of urea cycle for the detoxification and removal of ammonia. In non-small cell-lung cancer cells. SIRT5 contributions have also been observed for the cancer cell growth and drug resistance. Study shows that SIRT5 may possess oncogenic property.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500496.

技术参数 Specifications

biological source	chicken
Quality Segment	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
species reactivity	human, mouse
technique(s)	indirect ELISA: suitable,western blot: suitable
NCBI accession no.	NP_036373
UniProt accession no.	Q9NXA8
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... SIRT5(23408)

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