KD-Validated Anti Oxoglutarate receptor 1 Antibody, clone 23GB4575, Rabbit Monoclonal，1004G，SAB6012351-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 181-215 of human OXGR1 / GPR99 [NP_001333123.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

技术参数 Specifications

biological source	rabbit (Monoclonal)
Quality Segment	100
recombinant	expressed in HEK 293 cells
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	23GB4575, recombinant monoclonal
form	buffered aqueous glycerol solution
mol wt	38 kDa
species reactivity	human, rat
packaging	vial of 1.5 mL
enhanced validation	recombinant expression Learn more about Antibody Enhanced Validation
sustainability	Greener Alternative Product
concentration	0.8 mg/ml
technique(s)	flow cytometry: 1:2000,immunofluorescence: 1:100-:1000,western blot: 1:1,000-1:5,000
isotype	IgG
Ensembl \| human accession no.	ENSG00000165621
NCBI accession no.	NP_001333123.1
UniProt accession no.	Q96P68
greener alternative category	DfS-Developed
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... OXGR1(27199)

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