Anti-Phospho-PKCdelta-Y311 antibody produced in rabbit,100UL,SAB5700371-100UL,Sigma

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订货号 0BT1092
品牌型号 Sigma SAB5700371-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.


Immunogen

A phospho specific peptide corresponding to residues surrounding Y311 of human PKCdelta


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 77, 80
species reactivitymouse, human
concentration2.5 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt accession no.Q05655
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pTyr311)
Gene Informationhuman ... PRKCD(5580)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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