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- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
Cell penetrant, potent and selective covalent c-MYC inhibitor that targets cysteine 171
EN4 is a cell penetrant, potent and selective covalent c-MYC inhibitor that targets cysteine 171 located within a predicted intrinsically disordered region of MYC. EN4 inhibits MYC transcriptional activity, downregulates multiple MYC transcriptional targets, reduces MYC and MAX thermal stability, and impairs tumorigenesis.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(C1=CC=C(CNC(C=C)=O)C=C1)NC2=C(OC3=CC=C(OCC)C=C3)C=CC=C2 |
| InChI | 1S/C25H24N2O4/c1-3-24(28)26-17-18-9-11-19(12-10-18)25(29)27-22-7-5-6-8-23(22)31-21-15-13-20(14-16-21)30-4-2/h3,5-16H,1,4,17H2,2H3,(H,26,28)(H,27,29) |
| InChI key | DKOWGKKELPCHEG-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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