Anti-COX1/PTGS1 Antibody, clone 8L4X10, Rabbit Monoclonal,100UL,SAB5702442-100UL,Sigma

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订货号 0BT0840
品牌型号 Sigma SAB5702442-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human COX1/PTGS1 (P23219).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone8L4X10, monoclonal
formliquid
species reactivityrat, human
concentration0.33 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI
UniProt accession no.P23219
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PTGS1(5742)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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