- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
Cell penetrant, potent and selective nanomolar inhibitor of UDP-glucose ceramide glucosyltransferase (UGCG)
EtDO-P4, a ceramide analog, is a cell penetrant, potent and selective nanomolar inhibitor of UDP-glucose ceramide glucosyltransferase (UGCG). Inhibition of UGCG by EtDO-P4 decreases drug resistance and enhances cytotoxicity of chemotherapeutic drugs such as vincristine, daunorubicin, Lucena-1 and cisplatin.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | N3(CCCC3)C[C@@H](NC(=O)CCCCCCCCCCCCCCC)[C@H](O)c1cc2c(cc1)OCCO2 |
| InChI | 1S/C31H52N2O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-30(34)32-27(25-33-20-15-16-21-33)31(35)26-18-19-28-29(24-26)37-23-22-36-28/h18-19,24,27,31,35H,2-17,20-23,25H2,1H3,(H,32,34)/t27-,31-/m1/s1 |
| InChI key | BBTZZVJOQCCAOR-DLFZDVPBSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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