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产品介绍
Product Description
Biochem/physiol Actions
NK-252 is a very potent, specific activator of the transcription factor Nrf2, which activates antioxidant-associated genes. NK-252 induces expression of an antioxidant response element promoter driven reporter gene, and protects Huh-7 liver cells against H202 induced cytotoxicity.
NK-252 is a very potent, specific activator of the transcription factor Nrf2.
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | N(Cc3ncccc3)C(=O)Nc1nnc([o]1)c2[o]ccc2 |
| InChI | 1S/C13H11N5O3/c19-12(15-8-9-4-1-2-6-14-9)16-13-18-17-11(21-13)10-5-3-7-20-10/h1-7H,8H2,(H2,15,16,18,19) |
| InChI key | FNSCFQXZZNCDAI-UHFFFAOYSA-N |
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