Anti-Phospho-FAK-Y576/577 antibody produced in rabbit,100UL,SAB5701885-100UL,Sigma

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订货号 0BS9818
品牌型号 Sigma SAB5701885-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015]


Immunogen

A synthetic phosphorylated peptide around Y925 of human FAK (NP_722560.1).


Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivityrat, mouse, human
concentration2.91 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt accession no.Q05397
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pTyr576/pTyr577)
Gene Informationhuman ... PTK2(5747)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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