Monoclonal Anti-CD56 PE-Cyanine7 produced in mouse,100YL4,SAB4702046-100TST,Sigma

销售价: ¥ 2437.88 / 件
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订货号 0BS8464
品牌型号 Sigma SAB4702046-100TST
货期 询货期
最小订货量 1件
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  • 商品介绍
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产品介绍 Product Description

General description

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.


Immunogen

Cell line KG1a


Biochem/physiol Actions

The mouse monoclonal antibody LT56 recognizes an extracellular epitope of CD56 (NCAM), a transmembrane glycoprotein expressed ubiquitously in the nervous system and found also on T cells and NK cells.


Physical form

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide


Preparation Note

Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 7 (PE-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.


Other Notes

The antibody solution should be gently mixed before use.


技术参数 Specifications
conjugatePE-Cy7 conjugate
Quality Segment100
antibody product typeprimary antibodies
cloneLT56, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)flow cytometry: suitable
isotypeIgG2a
UniProt accession no.P13591
storage temp.2-8°C
target post-translational modificationunmodified
Gene Informationhuman ... NCAM1(4684)
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