Anti-14-3-3 epsilon Antibody, clone 4X6E1, Rabbit Monoclonal,100UL,SAB5702558-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BS8426
品牌型号 Sigma SAB5702558-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 epsilon (P62258).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone4X6E1, monoclonal
formliquid
mol wt 28 kDa
species reactivityhuman, rat
concentration0.2 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDI
UniProt accession no.P62258
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... YWHAE(7531)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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