- 商品介绍
- 规格参数
- 包装参数
Application
BAY 41-2272 has been used for the stimulation of guanylate cyclase in heart and neurons.
Biochem/physiol Actions
BAY 41-2272 is an activator of soluble guanylate cyclase at a novel, NO-independent regulatory site. BAY 41-2272 is the first product that stimulates sGC through a non-NO mechanism. BAY 41-2272 inhibits platelet aggregation and induces vasorelaxation without nitrate tolerance.
BAY 41-2272 is an activator of soluble guanylate cyclase; stimulates sGC through a non-NO mechanism; inhibits platelet aggregation, and induces vasorelaxation without nitrate tolerance.
Features and Benefits
This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
| Quality Segment | 100 |
| assay | ≥97% (HPLC) |
| form | powder |
| color | white to light brown |
| mp | 210.5-211.4 °C |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| originator | Bayer |
| storage temp. | 2-8°C |
| SMILES string | Nc1nc(ncc1C2CC2)-c3nn(Cc4ccccc4F)c5ncccc35 |
| InChI | 1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25) |
| InChI key | ATOAHNRJAXSBOR-UHFFFAOYSA-N |
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