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Biochem/physiol Actions
ERGi-USU is a selective and potent inhibitor of growth of ERG positive cancer cell lines, while spearing normal prostate or endothelial cells. It potently inhibits growth of ERG positive VCaP xenografts in mice. ERGi-USU is a potent and selective ligand of the ribosomal atypical kinase RIOK2 (right open reading frame (RIO) kinase 2) that induces ribosomal stress.
potent and selective ligand of the ribosomal atypical kinase RIOK2; inhibitor of growth of ERG positive cancer cell lines
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | faint brown to dark red |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | [s]1c(ncc1)N=Nc2c3c(ccc2O)cccc3 |
| InChI | 1S/C13H9N3OS/c17-11-6-5-9-3-1-2-4-10(9)12(11)15-16-13-14-7-8-18-13/h1-8,17H |
| InChI key | IOMXCGDXEUDZAK-UHFFFAOYSA-N |
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¥ 1148.92
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¥ 2622.09
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¥ 1302.89
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¥ 1866.29
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¥ 2068.25
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¥ 1956.41
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¥ 4968.78
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔¥ 2856.42
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
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