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General description
Bruton tyrosine kinase (BTK) belongs to the Tec family of kinases. It is expressed in multiple hematopoietic cells. It plays a role in B-cell activation, maturation, development, and B-cell receptor (BCR)-signaling. Mutations in the BTK gene are associated with an inherited disorder, X-linked agammaglobulinemia. The BTK gene is located on the human chromosome at Xq22.1.
The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-BTK.
Application
请参考Protocol了解详情。
| species reactivity | human |
| technique(s) | ELISA: suitable |
| assay range | inter-assay cv: <10% intra-assay cv: <12% |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... BTK(695) |
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