KD-Validated Anti HNRNPM Antibody, clone 23GB4895, Rabbit Monoclonal,1004G,SAB6012359-100UL,Sigma

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订货号 0BN6750
品牌型号 Sigma SAB6012359-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 250-300 of human HNRNPM [NP_005959.2].


Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.


Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.


技术参数 Specifications
biological sourcerabbit (Monoclonal)
Quality Level100
recombinantexpressed in HEK 293 cells
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clone 23GB4895, recombinant monoclonal
formbuffered aqueous glycerol solution
mol wt 78 kDa
species reactivityhuman, rat
packagingvial of 1.5 mL
enhanced validationrecombinant expression
Learn more about Antibody Enhanced Validation
sustainabilityGreener Alternative Product
concentration1.2 mg/ml
technique(s)flow cytometry: 1:2000,western blot: 1:1,000-1:5,000
isotypeIgG
Ensembl | human accession no.ENSG00000099783
NCBI accession no.NP_005959.2
UniProt accession no.P52272
greener alternative categoryDfS-Developed
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... HNRNPM(4670)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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