DUSP22, active, GST tagged human,10UG,SRP5021-10UG,Sigma

销售价: ¥ 4745.77 / 件
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订货号 : 0BS2123
品牌型号 : Sigma SRP5021-10UG
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Dual specificity phosphatases (DUSP) family, which can dephosphorylate both phosphoserine/threonine and phosphotyrosine residues, comprise of two subgroups: "typical" DUSP (include 11 MKPs that dephosphorylate the mitogen-activated protein kinases Erk, Jnk, and p38 at their dually phosphorylated TXY activation loop motif) and "atypical" DUSP (include 8 enzymes that lack specific MAP kinase-targeting motifs and tend to be much smaller proteins, which are less than 250 amino acid residues). DUSP22, also called JKAP, JSP1 and MKPX plays a role in various inflammatory and proliferative disorders associated with dysfunctional Jnk signaling.


Physical form

Supplied in 20mM MOPS, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 30% glycerol.


Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles


技术参数 Specifications
recombinantexpressed in E. coli
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
specific activity510-690 nmol/min·mg
mol wt ~43 kDa
NCBI accession no.NM_020185
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... DUSP22(56940)
长度(mm)
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