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Immunogen
Immunogen Description: Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin
Immunogen Region: C-terminal
Immunogen Species: Human
Immunogen type: Fusion protein
Application
Western blotting
Dilution 1:1000
Tissue/Cell Type Used: monkey COS-Beta-4-Spectrin-His
Immunofluorescence
Dilution 1:100
Tissue/Cell Type Used: SK-N-BE
Physical form
50% glycerol, 0.1% sodium azide
PBS pH 7.4
Preparation Note
Derived from animal serum
Protect from light; avoid repeated freeze-thaw cycles. Store at -20 °C long-term, 2-8 °C short-term.
Other Notes
Additional Product Details:
Does not cross react with other Beta-spectrins
Lot Expiration/Retest Date: Expires 1 year from purchase
Target/Gene Description: Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart . Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier .
Purification method: Protein G purified
Product type: Primary antibody
Antibody structure: Whole Antibody
Protein ID: NP_066022.2
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| conjugate | peroxidase conjugate |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | S393-2,monoclonal |
| description | clone S393-2, purified immunoglobulin, buffered aqueous solution,target molecular weight: 200 kDa |
| form | buffered aqueous solution |
| species reactivity | human (Tested), rat (Predicted), African green monkey (Tested), mouse (Predicted) |
| packaging | pkg of 100 μg |
| storage condition | avoid repeated freeze/thaw cycles,protect from light |
| concentration | 1.0 mg/mL |
| technique(s) | immunofluorescence: 1:100,western blot: 1:1000 |
| isotype | IgG1 |
| UniProt accession no. | Q9H254 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... SPTBN4(57731) |
| 长度(mm) | |
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¥ 1779.22
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¥ 3109.49
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¥ 238.17
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¥ 14407.09
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¥ 1568.60
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¥ 3335.66
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¥ 4011.97
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