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- 规格参数
- 包装参数
Application
Altanserin hydrochloride hydrate has been used in the pretreatment of rat brain samples and as a non-radioactive control in the calibration curve preparation for quantifying [18F]altanserin in high-performance liquid chromatography.
Altanserin hydrochloride hydrate is a specific 5-HT2/serotonergic antagonist and has been used in a study to assess serotonin release capacity in the human brain.
Biochem/physiol Actions
Altanserin hydrochloride hydrate is a specific 5-HT2/serotonergic antagonist.
The radioligand of altanserin, [18F]altanserin is useful as a positron emission tomography (PET)-radioligand for the visualization and quantification of serotonin2A (5-HT2A) receptors.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| solubility | DMSO: >5 mg/mL,H2O: insoluble |
| storage temp. | 2-8°C |
| SMILES string | O.Cl.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=S)Nc4ccccc4C3=O |
| InChI | 1S/C22H22FN3O2S.ClH.H2O/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;;/h1-8,16H,9-14H2,(H,24,29);1H;1H2 |
| InChI key | MFGBKMPKRJCLPK-UHFFFAOYSA-N |
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¥ 4862.67
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¥ 1125.70
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¥ 1987.51
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