KD-Validated Anti Syndecan binding protein Antibody, clone 23GB2185, Rabbit Monoclonal,1004G,SAB6012278-100UL,Sigma

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订货号 0BR8709
品牌型号 Sigma SAB6012278-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Jan 2017]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 2-79 of human Syntenin [NP_001007068.1].


Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.


Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.


技术参数 Specifications
biological sourcerabbit (Monoclonal)
Quality Segment100
recombinantexpressed in HEK 293 cells
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clone 23GB2185, recombinant monoclonal
formbuffered aqueous glycerol solution
mol wt 32 kDa
species reactivityhuman
packagingvial of 1.5 mL
enhanced validationrecombinant expression
Learn more about Antibody Enhanced Validation
sustainabilityGreener Alternative Product
concentration0.8 mg/ml
technique(s)flow cytometry: 1:2000,immunofluorescence: 1:100-:1000,western blot: 1:1,000-1:5,000
isotypeIgG
Ensembl | human accession no.ENSG00000137575
NCBI accession no.NP_001007068.1
UniProt accession no.O00560
greener alternative categoryDfS-Developed
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... SDCBP(6386)
长度(mm)
宽度(mm)
高度(mm)
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