Isobavachalcone,25MG,SML1450-25MG,Sigma

销售价: ¥ 4503.69 / 件
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订货号 0BR6282
品牌型号 Sigma SML1450-25MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Isobavachalcone is a chalcone isolated from multipurpose medical plant Psoralea corylifolia that inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cells. It appears that isobavachalcone modulates both MyD88-dependent and TRIF-dependent signaling of toll-like receptor 4 (TLR4). Isobavachalcone significantly inhibits both oligomerization and fibrillization of Aβ42. Isobavachalcone exhibits a wide spectrum of biological activities including antioxidative, antiplatelet, antimicrobial, anti-inflammatory, antitumor, and neuroprotective.
Isobavachalcone is a chalcone isolated from multipurpose medical plant Psoralea corylifolia that inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cells.


技术参数 Specifications
Quality Segment100
assay≥98% (HPCE)
formpowder
storage conditiondesiccated,protect from light
color white to beige
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.−20°C
SMILES stringOC1=C(CC=C(C)C)C(O)=C(C(/C=C/C2=CC=C(O)C=C2)=O)C=C1
InChI1S/C20H20O4/c1-13(2)3-9-16-19(23)12-10-17(20(16)24)18(22)11-6-14-4-7-15(21)8-5-14/h3-8,10-12,21,23-24H,9H2,1-2H3/b11-6+
InChI keyDUWPGRAKHMEPCM-IZZDOVSWSA-N
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