- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
EMPA is a potent, selective OX2R antagonist (IC50 = 2.3 nM). EMPA binds reversibly to OX2R and inhibits orexin-a and -b-evoked intracellular calcium flux in cells expressing recombinant OX2R, but not OX1R.
EMPA is a potent, selective OX2R antagonist.
Physical form
This product is solubilized for packaging and then dried down for shipment. It would appear as a lyophilized powder or film on the vial. Solvent should be added directly to the vial to prepare their sample for testing.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | film |
| color | white to light brown |
| storage temp. | −20°C |
| SMILES string | [S](=O)(=O)(N(CC(=O)N(CC)Cc3cnccc3)c2cnc(cc2)OC)c1c(cccc1)C |
| InChI | 1S/C23H26N4O4S/c1-4-26(16-19-9-7-13-24-14-19)23(28)17-27(20-11-12-22(31-3)25-15-20)32(29,30)21-10-6-5-8-18(21)2/h5-15H,4,16-17H2,1-3H3 |
| InChI key | KJPHTXTWFHVJIG-UHFFFAOYSA-N |
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