Anti-SARS-CoV Matrix antibody produced in rabbit,100UG,SAB3501116-100UG,Sigma

销售价: ¥ 4150.58 / 件
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订货号 0BR4482
品牌型号 Sigma SAB3501116-100UG
货期 询货期
最小订货量 1件
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  • 商品介绍
  • 规格参数
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产品介绍 Product Description

General description

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10.The membrane (M) protein or matrix protein is the most abundant structural protein and defines the shape of the viral envelope. It is an integral membrane protein involved in the budding of the viral particles and interacts with S (Spike) protein. It involves in organization of the nucleoprotein inside, which includes many copies of the N (nucleocapsid) protein bound to the genomic RNA. The M protein holds dominant cellular immunogenicity and has been determined as a protective antigen in humoral responses, which suggests it would serve as a potential target in vaccine design.


Immunogen

Anti-SARS-CoV-2/SARS-CoV Matrix antibody was raised against a peptide corresponding to 15 amino acids near the carboxy-terminus of SARS-CoV Matrix protein. The immunogen is located within the last 50 amino acids of SARS-CoV Matrix.


Application

Antibody validated: SARS-CoV-2/SARS-CoV Matrix antibody can be used for the detection of SARS-CoV-2/SARS-CoV Matrix protein in ELISA. It will detect 5 ng of free peptide at 1 μg/mL.


Physical form

Supplied in PBS containing 0.02% sodium azide.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivitySARS virus
concentration1 mg/mL
technique(s)ELISA: suitable,western blot: suitable
isotypeIgG
UniProt accession no.QHO62114.1
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene InformationSARS virus ... M(43740571)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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