Rabbit anti-G3BP1 Antibody, Affinity Purified,100UL,PLA0231-100UL,Sigma

销售价: ¥ 3909.04 / 件
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订货号 0BR2910
品牌型号 Sigma PLA0231-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Immunogen

The epitope recognized by PLA0231 maps to a region between residue 275 and 325 of human GTPase activating protein (SH3 domain) binding protein 1 using the numbering given in entry NP_005745.1 (GeneID 10146).


Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide


Other Notes

Ras-GAP SH3 domain binding protein (G3BP1) contains an RNA recognition motif (RRM) and an N-terminal nuclear transport factor 2-like (NTF2-like) domain. It was first identified in a screen for proteins that bind the SH3 domain of the Ras GTPase activating protein (RasGAP). It has been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation. G3BP1 is primarily cytoplasmic but has also been localized to the nucleus. G3BP1 has been shown to be overexpressed in human cancers.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity purified immunoglobulin
antibody product typeprimary antibodies
clonepolyclonal
species reactivitymouse, human
technique(s)immunoprecipitation (IP): 2-5 μg/mg,western blot: 1:2,000- 1:10,000
accession no.NP_005745.1
UniProt accession no.Q13283
shipped inwet ice
storage temp.2-8°C
target post-translational modificationunmodified
Gene Informationrabbit ... G3BP1(10146)
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