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Biochem/physiol Actions
CL097 is an imidazoquinoline (IMDQ) derivative (IQD) with dual toll-like receptor 7 & 8 (TLR7 & TLR8; TLR7/8) agonist activity. CL097 is commonly employed in the concentration range from 0.5 μg/mL to 45 μg/mL for stimulating cell surface TLR7/8 in cultures and is reported to be a stronger TLR7 ligand than CL075.
Imidazoquinoline (IMDQ) derivative (IQD) with dual toll-like receptor 7 & 8 (TLR7 & TLR8; TLR7/8) agonist activity. A stronger TLR7 ligand than CL075.
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to very dark brown |
| solubility | DMSO: 2 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| SMILES string | [nH]1c2c(nc1COCC)c(nc3c2cccc3)N |
| InChI | 1S/C13H14N4O/c1-2-18-7-10-16-11-8-5-3-4-6-9(8)15-13(14)12(11)17-10/h3-6H,2,7H2,1H3,(H2,14,15)(H,16,17) |
| InChI key | DEVCLHVFELRPIU-UHFFFAOYSA-N |
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¥ 1573.49
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¥ 8293.41
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¥ 3372.68
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¥ 4968.78
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¥ 1564.00
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¥ 8137.12
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¥ 2173.94
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¥ 58855.47
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¥ 25008.19
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