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General description
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen
A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
| biological source | rabbit |
| Quality Segment | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 36, 48, 49, 50, 52, 53, 54 |
| species reactivity | mouse, human, rat |
| concentration | 0.56 mg/ml |
| technique(s) | immunofluorescence: 1:20-1:100,western blot: 1:500-1:1000 |
| UniProt accession no. | P46937 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer127) |
| Gene Information | human ... YAP1(10413) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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