Monoclonal Anti-COX15 antibody produced in mouse,100UG,SAB1402734-100UG,Sigma

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订货号 0BR2292
品牌型号 Sigma SAB1402734-100UG
货期 询货期
最小订货量 1件
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  • 商品介绍
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产品介绍 Product Description

General description

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3′ region. (provided by RefSeq)


Immunogen

COX15 (NP_510870, 92 a.a. ~ 152 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LTESGLSMVDWHLIKEMKPPTSQEEWEAEFQRYQQFPEFKILNHDMTLTEFKFIWYMEYSH


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone2D2, monoclonal
formbuffered aqueous solution
mol wtantigen ~32.82 kDa
species reactivityhuman
technique(s)capture ELISA: suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
NCBI accession no.NM_078470
UniProt accession no.Q7KZN9
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... COX15(1355)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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