- 商品介绍
- 规格参数
- 包装参数
General description
Thyroid transcription factor-1 (TTF-1), also known as NK2 homeobox 1(NKX2-1), is a member of the NKx2 family of homeodomain transcription factors. It binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. TTF-1 is expressed in epithelial cells of the thyroid gland and the lung, and their derived tumors such as lung adenocarcinoma and small cell carcinomas and thyroid cancer. It is absent in mesotheliomas, breast cancer, and colon cancer.
Immunogen
Synthetic peptide derived from the internal region of human TTF-1 protein.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| recombinant | expressed in proprietary host |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | SP141, monoclonal |
| species reactivity | human (tested) |
| species reactivity (predicted by homology) | rat, mouse |
| technique(s) | flow cytometry: 1:100,immunohistochemistry: 1:100 |
| isotype | IgG |
| UniProt accession no. | P43699 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... NKX2-1(7080) |
| 长度(mm) | |
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| 重量(kg) |
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