Phospho-Stat3 (pTyr⁷⁰⁵) and pan-Stat3 ELISA Kit,1KIT,RAB0447-1KT,Sigma

销售价: ¥ 7022.14 / 件
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订货号 : 0BR1710
品牌型号 : Sigma RAB0447-1KT
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Signal transducers and activators of transcription 3 (STAT3) is a transcription factor that belongs to the family of STAT proteins. The protein contains an Src homology 2 (SH2) domain for protein-protein interactions. STAT3 is activated by phosphorylation on tyrosine 705 by c-Jun N-terminal kinases (JNKs), cytokine receptor-associated kinases, nonreceptor tyrosine kinases, and growth factor receptor tyrosine kinases, in response to growth factors and cytokines. Phosphorylation of STAT3 is important for dimer formation and gene expression. STAT3 mediates the expression of a variety of genes that are involved in cell proliferation and differentiation. It also aids in pro-cancer immunity. The Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA (enzyme-linked immunosorbent assay) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
The Phospho-Stat3 (pTyr705) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.


Immunogen

Stat3 (pTyr705) synthetic phosphopeptide, Recombinant Human Stat3


Application

Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) for quantitative measurement of phosphorylated signal transducer and activator of transcription3 (p-STAT3) in liver tissues.


技术参数 Specifications
species reactivityhuman, mouse, rat
technique(s)ELISA: suitable,capture ELISA: suitable
shipped inwet ice
storage temp.−20°C
Gene Informationhuman ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)
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