- 商品介绍
- 规格参数
- 包装参数
General description
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
Immunogen
Peptide sequence around phosphorylation site of threonine 18 (Q-E-T(p)-F-S), according to the protein TP53.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | ~53 kDa |
| species reactivity | human |
| concentration | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| isotype | IgG |
| immunogen sequence | (Q-E-TP-F-S) |
| NCBI accession no. | NP_000537.3 |
| UniProt accession no. | P04637 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pThr18) |
| Gene Information | human ... TP53(7157) |
| 长度(mm) | |
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¥ 2068.25
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¥ 4039.86
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¥ 4173.75
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¥ 8293.41
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¥ 3152.47
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¥ 238.17
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¥ 6330.00
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¥ 3290.05
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¥ 4897.21
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¥ 2666.57
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