纺锤霉素 二盐酸盐,5MG,N9653-5MG,Sigma

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订货号 0BR0084
品牌型号 Sigma N9653-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Netropsin is an unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin disrupts the cell cycle, prolonging G and arresting in G.


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Protect from light.


技术参数 Specifications
biological sourceStreptomyces netropsis
Quality Segment200
assay≥98% (HPLC)
formpowder
colorfaintly yellow
solubilityH2O: 1 mg/mL
antibiotic activity spectrumGram-negative bacteria,Gram-positive bacteria,viruses
mode of actionDNA synthesis | interferes
storage temp.−20°C
SMILES string[H]Cl.[H]Cl.NC(CCNC(C1=CC(NC(C2=CC(NC(CNC(N)=N)=O)=CN2C)=O)=CN1C)=O)=N
InChI1S/C18H26N10O3.2ClH/c1-27-9-11(6-12(27)16(30)23-4-3-14(19)20)26-17(31)13-5-10(8-28(13)2)25-15(29)7-24-18(21)22;;/h5-6,8-9H,3-4,7H2,1-2H3,(H3,19,20)(H,23,30)(H,25,29)(H,26,31)(H4,21,22,24);2*1H
InChI keySDRHUASONSRLFR-UHFFFAOYSA-N
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