Anti- macroH2A.1 antibody produced in rabbit,100UL,SAB5701635-100UL,Sigma

销售价: ¥ 4030.96 / 件
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订货号 0BQ9183
品牌型号 Sigma SAB5701635-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 123-372 of human H2AFY (NP_613258.2).


Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivityhuman, mouse
concentration1.43 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.O75367
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... H2AFY(9555)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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