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- 规格参数
- 包装参数
General description
Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle
Monoclonal Anti-Interleukin-2 recognizes murine Interleukin-2. It does not react with human IL-2, but will react with rabbit IL-2 at a 100x higher IgG concentration.
Immunogen
purified, E. coli-derived recombinant mouse interleukin-2.
Application
Anti-interleukin-2 antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml. The antibody is suitable for murine IL-2 neutralization assays.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
| biological source | goat |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | lyophilized powder |
| species reactivity | rat, mouse |
| technique(s) | neutralization: suitable,western blot: 0.1-0.2 μg/mL |
| UniProt accession no. | P04351 |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Il2(16183) rat ... Il2(116562) |
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¥ 1563.36
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¥ 1779.22
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¥ 1866.29
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¥ 3372.68
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¥ 4404.38
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