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产品介绍
Product Description
Biochem/physiol Actions
ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner.
ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner. ISCK03 inhibits SCF (stem cell factor)-induced c-kit phosphorylation in 501mel human melanoma cells. Complete inhibition was observed with 1 and 5 μM ISCK03.
Features and Benefits
This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| color | yellow |
| solubility | DMSO: ≥20 mg/mL,H2O: insoluble |
| storage temp. | 2-8°C |
| SMILES string | CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)-n3ccnc3 |
| InChI | 1S/C19H21N3O2S/c1-19(2,3)15-4-10-18(11-5-15)25(23,24)21-16-6-8-17(9-7-16)22-13-12-20-14-22/h4-14,21H,1-3H3 |
| InChI key | XQABBHBFHWHMKF-UHFFFAOYSA-N |
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