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- 规格参数
- 包装参数
Application
Salsalate was used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats.
Biochem/physiol Actions
NSAID; Nonacetylated aspirin analog
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to tan |
| solubility | DMSO: ≥15 mg/mL |
| storage temp. | room temp |
| SMILES string | OC(=O)c1ccccc1OC(=O)c2ccccc2O |
| InChI | 1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17) |
| InChI key | WVYADZUPLLSGPU-UHFFFAOYSA-N |
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¥ 1243.80
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¥ 1376.90
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¥ 839.71
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¥ 1518.67
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