MCOPPB trihydrochloride hydrate,5MG,PZ0159-5MG,Sigma

销售价: ¥ 1240.14 / 件
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订货号 0BQ7430
品牌型号 Sigma PZ0159-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

MCOPPB trihydrochloride is a potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. MCOPPB is the most potent novel non-peptide NOP full agonist in vitro and an orally potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.
Potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist.


Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


技术参数 Specifications
Quality Segment100
assay>98% (HPLC)
formpowder
storage conditiondesiccated
color white to tan
solubilityH2O: ≥13 mg/mL
storage temp.room temp
SMILES stringO.Cl.Cl.Cl.CC1(CCCCCCC1)N2CCC(CC2)n3c(nc4ccccc34)[C@@H]5CCCNC5
InChI1S/C26H40N4.3ClH.H2O/c1-26(15-7-3-2-4-8-16-26)29-18-13-22(14-19-29)30-24-12-6-5-11-23(24)28-25(30)21-10-9-17-27-20-21;;;;/h5-6,11-12,21-22,27H,2-4,7-10,13-20H2,1H3;3*1H;1H2
InChI keyUQBVSGBDJOJHIP-UHFFFAOYSA-N
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