TRKB (455-end), active, GST tagged human,10UG,T2080-10UG,Sigma

销售价: ¥ 4407.23 / 件
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订货号 0BQ5301
品牌型号 Sigma T2080-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TRKB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. TRKB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through TRKB leads to cell differentiation. Mutations in the TRKB gene have been associated with obesity and mood disorders.


Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.


Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
recombinantexpressed in baculovirus infected Sf9 cells
Quality Segment200
product linePRECISIO® Kinase
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
specific activity63-85 nmol/min·mg
mol wt ~67 kDa
UniProt accession no.Q16620
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... NTRK2(4915)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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