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Neuromedin U-23 (rat) trifluoroacetate，5MG，SML4019-5MG，Sigma

销售价： ¥ 4637.29 / 件

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订货号： 0BQ5128

品牌型号： Sigma SML4019-5MG

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最小订货量： 1件

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产品介绍 Product Description

Biochem/physiol Actions

Endogenous agonist of neuromedin-U receptor 1 (NMUR1) and neuromedin-U receptor 2 (NMUR2)

Neuromedin U-23 (Neuromedin U), a neuropeptide, is endogenous agonist of neuromedin-U receptor 1 (EC50 = 0.17 nM) and neuromedin-U receptor 2 (EC50 = 1.4 nM) that regulates blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function. Neuromedin U-23 decreases body weight and food intake and increases core body temperature in mice when administered at a dose of 36 µg/animal. It appears that neuromedin U regulates epithelial cell differentiation and barrier immunity through interaction with neuromedin-U receptor 1 present at small intestine eosinophils.

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Hygroscopic

技术参数 Specifications

Quality Segment	100
assay	≥95% (HPLC)
form	(Powder or Lyophilized powder or film)
storage condition	desiccated
color	white to off-white
storage temp.	-10 to -25°C
SMILES string	O=C([C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@@H](NC([C@@H](NC(CNC(CNC([C@H](CO)NC([C@H]2CCCN2C([C@@H](NC([C@H](C(C)C)NC(C3N(CCC3)C(CNC([C@@H](NC([C@H](CC4=CC=C(C=C4)O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@@H](N)CC5=CC=C(C=C5)O)=O)=O)C(C)C)=O)

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