ANTI-RPS6KB1 antibody produced in mouse,100UG,SAB1412617-100UG,Sigma

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订货号 0BQ5002
品牌型号 Sigma SAB1412617-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. (provided by RefSeq)


Immunogen

RPS6KB1 (NP_003152, 416 a.a. ~ 525 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
PSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone2C2, monoclonal
formbuffered aqueous solution
mol wtantigen 37.84 kDa
species reactivityhuman,
technique(s)indirect ELISA: suitable,indirect immunofluorescence: suitable,western blot: 1-5 μg/mL
isotypeIgG1κ
NCBI accession no.NM_003161
UniProt accession no.P23443
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... RPS6KB1(6198)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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