- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Application
Calhex 231 hydrochloride has been used:
- as a calcium-sensing receptor (CaSR) antagonist: to test its impact on hearing in rats
- to test its effect on blood pressure levels spontaneous hypertensive rats (SHRs)
- to test its effect on acoustic response bias in zebrafish
- in Caco-2 cells to test its effect on, overexpression of fibroblast growth factor-23 (FGF-23 )
Biochem/physiol Actions
Calhex 231 is a negative allosteric modulator of the calcium sensing receptor CaSR.
Calhex 231 is a negative allosteric modulator of the calcium sensing receptor CaSR. Calhex 231 blocks calcium-induced accumulation of inositol phosphate with an IC50 of 0.36 μM.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | DMSO: 15 mg/mL, clear |
| storage temp. | −20°C |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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