- 商品介绍
- 规格参数
- 包装参数
Application
Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) has been used as a caspase inhibitor to study its effects on lactate dehydrogenase (LDH) leakage, apoptosis and virus proliferation in chorion cells , as a component of the transplantation medium for the transplantation of human embryonic stem cells (ESC)-derived medial ganglionic eminence (MGE) cells into hippocampus of mice , as a protease inhibitor to study its effects on cell death in parasites .
Biochem/physiol Actions
Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) permits cell permeability. It is a caspase inhibitor and suppresses apoptosis induced by various kinds of stimuli. Boc-D-fmk poorly inhibits caspases-2, -5, -6 and -10.
| Quality Segment | 100 |
| assay | ≥90% (TLC) |
| form | solid |
| solubility | DMF: soluble |
| storage temp. | −20°C |
| SMILES string | COC(=O)C[C@H](NC(=O)OC(C)(C)C)C(=O)CF |
| InChI | 1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)/t7-/m0/s1 |
| InChI key | MXOOUCRHWJYCAL-ZETCQYMHSA-N |
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询价
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¥ 1048.84
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¥ 503.76
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¥ 807.83
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¥ 1243.80
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¥ 3317.36
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¥ 2355.14
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¥ 1153.44
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¥ 1958.88
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¥ 462.77
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¥ 1147.95
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¥ 3963.81
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