- 商品介绍
- 规格参数
- 包装参数
General description
Transmembrane member 16A (TMEM16A) or Anoctamin1 (Ano1) is a calcium-activated chloride channel. It is expressed in the interstitial cells of Cajal (ICC) in the gastrointestinal tract. The gene encoding this protein is localized on human chromosome 11q13.3.
Immunogen
TMEM16A antibody was raised against a 17 amino acid peptide from near the amino terminus of human TMEM16A.
Biochem/physiol Actions
Transmembrane member 16A (TMEM16A) or Ano1 is crucial for normal electrical slow waves and for the proliferation of interstitial cells of Cajal (ICC). The protein has a role in smooth muscle contraction, salivary secretion and cardiac and neuronal excitability. TMEM16A has been associated with head and neck squamous cell carcinoma and breast cancer.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied in PBS with 0.02% sodium azide.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3500318.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | mouse, human |
| technique(s) | indirect ELISA: suitable,western blot: suitable |
| NCBI accession no. | NP_060513 |
| UniProt accession no. | Q5XXA6 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... ANO1(55107) |
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¥ 95.27
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¥ 1349.07
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