- 商品介绍
- 规格参数
- 包装参数
Application
SU 4312 was used to study angiogenesis during development of zebrafish embryos.2
Biochem/physiol Actions
SU 4312 inhibits the neuronal NOS and exhibits neuroprotection against NO-mediated neurotoxicity. It might be effective in treatment of neurodegenerative disorders.1
SU 4312 is a vascular endothelial growth factor (VEGF) receptor protein tyrosine kinase 1/2 and platelet derived growth factor (PDGF) receptor inhibitor.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Other Notes
This product is a mixture of the cis- and trans- isomers. The ratio is about 55:45 based on HPLC.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | orange |
| solubility | DMSO: >10 mg/mL,H2O: insoluble |
| storage temp. | 2-8°C |
| SMILES string | CN(C)c1ccc(cc1)\C=C2\C(=O)Nc3ccccc23 |
| InChI | 1S/C17H16N2O/c1-19(2)13-9-7-12(8-10-13)11-15-14-5-3-4-6-16(14)18-17(15)20/h3-11H,1-2H3,(H,18,20)/b15-11+ |
| InChI key | UAKWLVYMKBWHMX-RVDMUPIBSA-N |
| Gene Information | human ... FLT1(2321) |
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| 重量(kg) |
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