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产品介绍
Product Description
Biochem/physiol Actions
DN02 is a potent and selective BRD8 first bromodomain inhibitor (BRD8(1) IC50 = 48 nM, BRD4(1) & BRD9 IC50 ≥10 μM; Kd = 34 nM/BRD8(1), >1 μM/BRD8(2), CBP, p300) that serves as a useful chemical probe for the selective engagement of BRD8 and enrichment of native NuA4 complexes.
Potent and selective BRD8 first bromodomain inhibitor for probing the engagement of BRD8 and enrichment of native NuA4 complexes.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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