抗-胰岛素样生长因子-I单克隆抗体 仓鼠抗,500UG,I9409-500UG,Sigma

销售价: ¥ 8610.57 / 件
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订货号 0BP8748
品牌型号 Sigma I9409-500UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Insulin-like Growth Factor-I (also known as somatomedinC and somatomedin A) and insulin-like growth factor-II(IGF-II) belong to the family of insulin-like growthfactors, which are structurally homologous to proinsulin.Mature IGF-I and IGF-II are h


Immunogen

purified, E. coli-derived recombinant mouse insulin-like growth factor-I.


Biochem/physiol Actions

Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades. The effects of IGF-1R signaling are important at many developmental levels from cells to organ to organism, growth, differentiation, anti-apoptosis, proliferation and transformation.


Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcehamster
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone126002, monoclonal
formlyophilized powder
species reactivitymouse
technique(s)capture ELISA: 2-8 μg/mL,neutralization: suitable,western blot: 1-2 μg/mL
isotypeIgG1
UniProt accession no.P05017
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationmouse ... Igf1(16000)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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